Drostanolone
Drostanolone is an anabolic-androgenic steroid (AAS) primarily used in medicine and bodybuilding. It is most commonly available in its esterified form, drostanolone propionate, and sold under brand names such as Masteron. Drostanolone is a derivative of dihydrotestosterone (DHT), which gives it unique properties compared to other AAS.
Key Characteristics
Chemical Information:
Chemical Name: 2α-methyl-5α-androstan-17β-ol-3-one.
Molecular Formula: C20H32O2.
Molecular Weight: 304.47 g/mol.
Derivation: Modified from dihydrotestosterone (DHT) with an added methyl group at the carbon-2 position, enhancing anabolic activity.
Available Forms:
Drostanolone Propionate: Short-acting ester with a half-life of 2–3 days.
Drostanolone Enanthate: Long-acting ester with a half-life of 5–7 days.
Mechanism of Action
Drostanolone binds to androgen receptors in target tissues, such as muscles and the central nervous system, to exert its effects:
Inhibits Aromatase Activity: Unlike other steroids, drostanolone does not convert into estrogen, making it effective in reducing water retention and minimizing the risk of gynecomastia.
Enhances Protein Synthesis: Promotes muscle growth by increasing nitrogen retention and protein building.
Boosts Red Blood Cell Production: Improves oxygen transport to muscles, aiding endurance and recovery.
Medical Uses
Breast Cancer Treatment: Drostanolone was initially developed to treat estrogen-sensitive breast cancer in women. Its anti-estrogenic properties made it effective in this role, though it is no longer widely used for this purpose due to the development of more targeted therapies.
Cachexia Management: Occasionally used off-label for conditions involving severe muscle wasting.
Use in Bodybuilding and Athletics
Drostanolone is popular among bodybuilders for its aesthetic and performance-enhancing properties:
Cutting Cycles: Used to maintain muscle mass while reducing body fat.
Dry, Hard Appearance: Its non-aromatizing nature contributes to a lean, sculpted physique by eliminating water retention.
Performance Enhancement: Improves strength and recovery without significant weight gain, making it a favorite in sports requiring weight classes.
Common Doses (Illicit Use):
Men: 300–600 mg per week.
Women: 50–100 mg per week (to minimize virilization).
Typical cycle duration: 6–10 weeks.
Potential Side Effects
Androgenic Effects:
Acne, oily skin, and increased facial/body hair.
Male-pattern baldness (in genetically predisposed individuals).
Virilization in women (deepened voice, clitoral enlargement, etc.).
Cardiovascular Issues:
Negative impact on cholesterol: Decreased HDL ("good cholesterol") and increased LDL ("bad cholesterol").
Increased risk of cardiovascular disease with prolonged use.
Hormonal Effects:
Suppression of natural testosterone production, leading to dependence on post-cycle therapy (PCT) to restore hormonal balance.
Psychological Effects:
Possible mood swings, aggression, or irritability.
Hepatotoxicity:
Drostanolone is not significantly hepatotoxic but can strain the liver when used in high doses or stacked with other substances.
As one of the leading drostanolone manufacturers and suppliers in China, we warmly welcome you to buy cost-efficient drostanolone for sale here from our factory. All our products are with high quality and competitive price.
Nootropic, GW0742, S 4 Raw Powder