1, 4-Butanediol BDO

1, 4-Butanediol BDO Basic Information

 

Product Name: 1,4-Butanediol

Synonyms: 1,4 BDO; BDO

CAS: 110-63-4

MF: C4H10O2

MW: 90.12

Category: Solvents

Solubility: 1,4-Butanediol is soluble in water, alcohols, esters, ketones, glycol ethers and glycol ether acetates (Butanediols, Butenediol, and Butynediol).

Form: Odorless colorless liquid

1,4-Butanediol is a chemical. It's used as a source of gamma-hydroxybutyrate (GHB), a recreational drug with euphoric and sedative effects.

1,4-Butanediol is converted to GHB in the body. GHB slows down the brain, which can cause loss of consciousness along with dangerous slowing of breathing and other vital functions.

People use 1,4-Butanediol for muscle strength, obesity, insomnia, and other purposes, but there is no good scientific evidence to support any use. It is also unsafe.

1,4-butanediol is converted to gamma-hydroxybutyric acid (GHB) by two of alcohol metabolism enzymes when ingested. GHB is a central nervous system depressant denoted by the DEA (Drug Enforcement Agency) as a Schedule I controlled substance. The effects of GHB include euphoria, drowsiness, decreased anxiety, confusion and memory impairment. Because our bodies can convert 1,4-butanediol to GHB, 1,4-butanediol is also regulated. Please see the ACC American Chemistry Council, GLB/BDO Panel Guide for Industrial Users.

1,4-butanediol (1,4-BD) is a colorless, viscous liquid derived from butane by placement of alcohol groups at each end of its molecular chain and is one of four stable isomers of butanediol.the hydroxyl function of each end group of the Butanediol reacts with different mono- and bifunctional reagents: for example with dicarboxylic acids to polyesters, with diisocyanates to polyurethanes, or with phosgene to polycarbonates. 1.4-Butanediol (BDO) is a high-quality intermediate. BDO and its derivatives are widely used for producing plastics, solvents, electronic chemicals and elastic fibers. Additionally BDO is also a building block for the synthesis of polyesterpolyols and polyetherpolyols. BASF is the most significant producer of 1,4-Butanediol and its derivatives worldwide.

When taken by mouth: 1,4-Butanediol is unsafe. It has been linked with very serious side effects, including trouble breathing, tremors, hallucinations, and death.

1. Butanediol and its derivatives is used in a broad spectrum of applications in the chemical industry; amongst others in the manufacturing of technical plastics, polyurethanes, solvents, electronic chemicals and elastic fibres.
2. 1,4-Butanediol is used in the synthesis of epothilones, a new class of cancer drugs. Also used in the stereoselective synthesis of (-)-Brevisamide.
3. 1,4-Butanediol's largest use is within tetrahydrofuran (THF) production, used to make polytetramethylene ether glycol, which goes mainly into spandex fibers, urethane elastomers, and copolyester ethers.
4. It is commonly used as a solvent in the chemical industry to manufacture gamma-butyrolactone and elastic fibers like spandex.
5. It is used as a cross-linking agent for thermoplastic urethanes, polyester plasticizers, paints and coatings.
6. It undergoes dehydration in the presence of phosphoric acid yielded teterahydrofuran, which is an important solvent used for various applications.
7. It acts an intermediate and is used to manufacture polytetramethylene ether glycol (PTMEG), polybutylene terephthalate (PBT) and polyurethane (PU).
8. It finds application as an industrial cleaner and a glue remover.
9. 1,4-butanediol is also used as a plasticiser (e.g. in polyesters and cellulosics), as a carrier solvent in printing ink, a cleaning agent, an adhesive (in leather, plastics, polyester laminates and polyurethane footwear), in agricultural and veterinary chemicals and in coatings (in paints, varnishes and films).

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