Semaglutide Basic Information
Product Name: Semaglutide
Synonyms: Sermaglutide; Semaglutide
CAS: 910463-68-2
MF: C187H291N45O59
MW: 4113.57754
EINECS: 203-405-2
Solubility DMSO: 3mg/mL (0.73 mM)
What is semaglutide?
Semaglutide belongs to a class of medications known as glucagon-like peptide-1 receptor agonists, or GLP-1 RAs. It mimics the GLP-1 hormone, released in the gut in response to eating.
One role of GLP-1 is to prompt the body to produce more insulin, which reduces blood sugar (glucose). For that reason, health care providers have used semaglutide for more than 15 years to treat Type 2 diabetes.
But GLP-1 in higher amounts also interacts with the parts of the brain that suppress your appetite and signal you to feel full. When used in conjunction with diet and exercise, it can cause significant weight loss - and a reduced risk of cancer, diabetes and heart disease - in people who are obese or overweight.
Semaglutide injections for weight loss
Currently, semaglutide is only approved for weight loss. The typical dose for weight loss is 2.4 milligrams, administered weekly as subcutaneous (under the skin) self-injections.
This medication is for injection under the skin of your upper leg (thigh), stomach area, or upper arm. It is given once every week (every 7 days). You will be taught how to prepare and give this medication. Use exactly as directed. Take your medication at regular intervals. Do not take it more often than directed.
If you use this medication with insulin, you should inject this medication and the insulin separately. Do not mix them together. Do not give the injections right next to each other. Change (rotate) injection sites with each injection.
What are the side effects of semaglutide injections?
The side effects of semaglutide are typically mild - especially when compared to the complications associated with overweight and obesity.
People taking semaglutide for weight loss may experience:
- Dizziness
- Fatigue
- Gastrointestinal issues, such as diarrhea, constipation and gassiness
- Headache
- Stomach issues, including nausea, vomiting, pain or distension (bloat)
Gastrointestinal issues are the most common complaint among people just starting semaglutide. But you may be able to reduce the side effects by beginning on a lower dose and then slowly increasing the amount you take.
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