Tamoxifen Citrate

Tamoxifen citrate Basic Information

 

Product Name: Tamoxifen Citrate

Alias: Tamoxifen, Nolvadex

CAS Registry Number: 54965-24-1

Assay: 98%+

Molecular Formula: C26H29NO.C6H8O7

Molecular weight: 563.64

MP: 140-144 ºC

Appearance: white powder

Tamoxifen citrate (Nolvadex) is a non-steroidal agent that demonstrates potent antiestrogenic properties. The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues.

Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow.

Tamoxifen is used to treat some types of breast cancer in men and women.

Tamoxifen is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer).

Tamoxifen is a selective estrogen receptor modulator (SERM) used:

• After surgery to reduce the risk of hormone receptor-positive, early-stage breast cancer coming back (recurring) in women or men
• To treat advanced-stage, hormone receptor-positive breast cancer in women or men
• After surgery to reduce the risk of invasive breast cancer in women diagnosed with hormone receptor-positive DCIS (ductal carcinoma in situ)
• To reduce the risk of breast cancer in women with a higher-than-average risk of the disease who haven't been diagnosed

Tamoxifen blocks the effects of estrogen on hormone receptor-positive breast cancer cells by sitting in the estrogen receptors on the cells. If tamoxifen is in the receptor, estrogen can't attach to the cancer cell and the cell doesn't receive estrogen's signals to grow and multiply.

Tamoxifen won't work on hormone receptor-negative breast cancer.

Tamoxifen has been used to treat hormone receptor-positive breast cancer in millions of women and men. Although an aromatase inhibitor usually is the first hormonal therapy medicine choice for post-menopausal women, tamoxifen is the first choice for pre-menopausal women and is still a good choice for post-menopausal women who can't take an aromatase inhibitor.

Tamoxifen can:

reduce the risk of breast cancer coming back by 40% to 50% in post-menopausal women and by 30% to 50% in pre-menopausal women

reduce the risk of a new cancer developing in the other breast by about 50%

Tamoxifen offers other health benefits that aren't related to treating cancer. Because it's a SERM, it selectively either blocks or activates estrogen's action on specific cells. While tamoxifen blocks estrogen's action on breast cells, it also activates estrogen's action in bone and liver cells. So tamoxifen can:

• Help stop bone loss after menopause
• Lower cholesterol levels

Nolvadex and Clomid are two of the most popular Selective Estrogen Receptor Modulators (SERMs) in the world and part of the supplemental plan for many performance enhancing athletes. More athletes buy Nolvadex for PCT purposes than any other purpose; in-fact, more performance enhancers buy Nolvadex for their PCT use than any other medication available.

In-fact, more performance enhancers buy Nolvadex for their PCT use than any other medication available. As you understand the purpose of the PCT period is to stimulate natural testosterone production after a cycle of anabolic steroids has been discontinued; this is necessary as anabolic steroids suppress natural testosterone production. Further, beyond testosterone stimulation this is the period when we begin normalizing our body but in the case of Tamoxifen Citrate it is testosterone production we are concerned with here.

Gynecomastia(male breast enlargement) is one of the most worrisome side-effects that can occur due to anabolic androgenic steroid use, fortunately you can buy Nolvadex and combat this effect; no, Tamoxifen Citrate will not reduce the amount of estrogen in your body but it will prevent a large portion of it from binding and this provides protectio.

The average Nolvadex dosage can vary quite dramatically depending the purpose of use as well as whos using it. In most cases the compound comprised of Tamoxifen Citrate will be used for on cycle side-effect prevention, Post Cycle Therapy (PCT) and by females for a testosterone boosting effect or as part of a physique competition preparation. In any case the average Nolvadex dosage will range from 10mg to 40mg and in most cases never exceed this mark.

For most women the most common Nolvadex dosage will be at 10mg per day with very few ever exceeding 20mg per day and most will never need this much.

The purpose of use during PCT is simple; to stimulate natural testosterone production that has been suppressed due to anabolic steroid use and more than likely tremendously so. For most men daily therapy will begin at 40mg per day, eventually dropping to 20mg per day until use is discontinued. The average man will need at least 4 weeks of total therapy with many men needing 6 total weeks if their steroid cycle was long and suppressive in nature. However long your PCT plan is a Nolvadex dosage of 40mg per day for the first half of the plan followed by a 20mg every day the final weeks will suffice.

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